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Positron Emission Tomography Imaging of the Gastrin-Releasing Peptide Receptor with a Novel Bombesin Analogue

[Image: see text] The gastrin-releasing peptide receptor (GRPR), a G protein-coupled receptor, is overexpressed in solid malignancies and particularly in prostate cancer. We synthesized a novel bombesin derivative, [(68)Ga]Ga-ProBOMB1, evaluated its pharmacokinetics and potential to image GRPR expre...

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Detalles Bibliográficos
Autores principales: Lau, Joseph, Rousseau, Etienne, Zhang, Zhengxing, Uribe, Carlos F., Kuo, Hsiou-Ting, Zeisler, Jutta, Zhang, Chengcheng, Kwon, Daniel, Lin, Kuo-Shyan, Bénard, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372246/
https://www.ncbi.nlm.nih.gov/pubmed/30775647
http://dx.doi.org/10.1021/acsomega.8b03293