Cargando…
Prevalence of DNA repair gene mutations in localized prostate cancer according to clinical and pathologic features: Association of Gleason score and tumor stage
BACKGROUND: DNA repair gene mutations are present in 8–10% of localized prostate cancers. It is unknown if this is influenced by clinicopathologic factors. METHODS: We interrogated localized prostate adenocarcinomas with tumor DNA sequencing from the TCGA validated (n=333) and Nature Genetics (n=377...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372344/ https://www.ncbi.nlm.nih.gov/pubmed/30171229 http://dx.doi.org/10.1038/s41391-018-0086-1 |