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Measurement of the Spatial Distribution of S1P in Small Quantities of Tissues: Development and Application of a Highly Sensitive LC-MS/MS Method Combined with Laser Microdissection

Sphingosine-1-phosphate (S1P) acts as an extracellular signaling molecule with diverse biological functions. Tissues appear to have an S1P gradient, which is functionally relevant in the biological significance of S1P, although its existence has not been measured directly. Here, we report a highly s...

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Detalles Bibliográficos
Autores principales: Wang, Jiao, Kano, Kuniyuki, Saigusa, Daisuke, Aoki, Junken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Mass Spectrometry Society of Japan 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372364/
https://www.ncbi.nlm.nih.gov/pubmed/30805275
http://dx.doi.org/10.5702/massspectrometry.A0072