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Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis

Argonaute2 (AGO2) is an effector of small RNA mediated gene silencing. Increasing evidence show that post-translational modifications of AGO2 can change miRNA activity at specific or global levels. Among the six mature miRNAs that are encoded by miR-17-92, miR-19b1 is the most powerful to exert the...

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Detalles Bibliográficos
Autores principales: Zhang, Hailong, Wang, Yanli, Dou, Jinzhuo, Guo, Yanmin, He, Jianfeng, Li, Lian, Liu, Xiaojia, Chen, Ran, Deng, Rong, Huang, Jian, Xie, Ruiyu, Zhao, Xian, Yu, Jianxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372475/
https://www.ncbi.nlm.nih.gov/pubmed/30305728
http://dx.doi.org/10.1038/s41388-018-0530-7