Cargando…

Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis

Argonaute2 (AGO2) is an effector of small RNA mediated gene silencing. Increasing evidence show that post-translational modifications of AGO2 can change miRNA activity at specific or global levels. Among the six mature miRNAs that are encoded by miR-17-92, miR-19b1 is the most powerful to exert the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Hailong, Wang, Yanli, Dou, Jinzhuo, Guo, Yanmin, He, Jianfeng, Li, Lian, Liu, Xiaojia, Chen, Ran, Deng, Rong, Huang, Jian, Xie, Ruiyu, Zhao, Xian, Yu, Jianxiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372475/ https://www.ncbi.nlm.nih.gov/pubmed/30305728 http://dx.doi.org/10.1038/s41388-018-0530-7

Ejemplares similares

miR186 suppresses prostate cancer progression by targeting Twist1
por: Zhao, Xian, et al.
Publicado: (2016)

Hypoxia regulates overall mRNA homeostasis by inducing Met(1)-linked linear ubiquitination of AGO2 in cancer cells
por: Zhang, Hailong, et al.
Publicado: (2021)

SUMO1 modification of KHSRP regulates tumorigenesis by preventing the TL-G-Rich miRNA biogenesis
por: Yuan, Haihua, et al.
Publicado: (2017)

SUMOylation of Csk Negatively Modulates its Tumor Suppressor Function
por: Cui, Nan, et al.
Publicado: (2019)

AGO2 phosphorylation by c-Src kinase promotes tumorigenesis
por: Liu, Tianqi, et al.
Publicado: (2020)

SUMOylation of TARBP2 regulates miRNA/siRNA efficiency
por: Chen, Cheng, et al.
Publicado: (2015)

BAP1 suppresses prostate cancer progression by deubiquitinating and stabilizing PTEN
por: Deng, Rong, et al.
Publicado: (2020)

Src SUMOylation Inhibits Tumor Growth Via Decreasing FAK Y925 Phosphorylation
por: Wang, Jing, et al.
Publicado: (2017)

SUMOylation modulates the LIN28A‐let‐7 signaling pathway in response to cellular stresses in cancer cells
por: Dou, Jinzhuo, et al.
Publicado: (2020)

SUMOylation of the m(6)A-RNA methyltransferase METTL3 modulates its function
por: Du, Yuzhang, et al.
Publicado: (2018)

SUMOylation at K(707) of DGCR8 controls direct function of primary microRNA
por: Zhu, Changhong, et al.
Publicado: (2015)

Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors
por: Xu, Ming, et al.
Publicado: (2014)

Correction: Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors
por: Xu, Ming, et al.
Publicado: (2019)

AGO1 and AGO2 Act Redundantly in miR408-Mediated Plantacyanin Regulation
por: Maunoury, Nicolas, et al.
Publicado: (2011)

Modulation of oncogenic miRNA biogenesis using functionalized polyamines
por: Staedel, Cathy, et al.
Publicado: (2018)

eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference
por: Yi, Tingfang, et al.
Publicado: (2015)

Chilling Stress Triggers VvAgo1-Mediated miRNA-Like RNA Biogenesis in Volvariella volvacea
por: Gong, Ming, et al.
Publicado: (2020)

The miR-183 Cluster: Biogenesis, Functions, and Cell Communication via Exosomes in Cancer
por: Li, Shuhui, et al.
Publicado: (2023)

CSDE1 promotes miR-451 biogenesis
por: Kakumani, Pavan Kumar, et al.
Publicado: (2023)

Unexpected Implication of SRP and AGO2 in Parkinson’s Disease: Involvement in Alpha-Synuclein Biogenesis
por: Hernandez, Sarah M., et al.
Publicado: (2021)

miR-98-5p contributes to cisplatin resistance in epithelial ovarian cancer by suppressing miR-152 biogenesis via targeting Dicer1
por: Wang, Yanan, et al.
Publicado: (2018)

SUMOylation of YTHDF2 promotes mRNA degradation and cancer progression by increasing its binding affinity with m(6)A-modified mRNAs
por: Hou, Guofang, et al.
Publicado: (2021)

p62 acts as an oncogene and is targeted by miR-124-3p in glioma
por: Deng, Danni, et al.
Publicado: (2019)

miR-346 and miR-138 competitively regulate hTERT in GRSF1- and AGO2-dependent manners, respectively
por: Song, Ge, et al.
Publicado: (2015)

KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression
por: Zhao, Hongmei, et al.
Publicado: (2017)

miR-122 and Ago interactions with the HCV genome alter the structure of the viral 5′ terminus
por: Chahal, Jasmin, et al.
Publicado: (2019)

PTBP1 enhances miR-101-guided AGO2 targeting to MCL1 and promotes miR-101-induced apoptosis
por: Cui, Jia, et al.
Publicado: (2018)

Analysis on Value of Applying Serum miR-144 and miR-221 Levels in Diagnosing Atherosclerosis
por: Zhang, Jianxiu, et al.
Publicado: (2022)

Miravirsen (SPC3649) can inhibit the biogenesis of miR-122
por: Gebert, Luca F. R., et al.
Publicado: (2014)

Distinct AGO1 and AGO2 associated miRNA profiles in human cells and blood plasma
por: Turchinovich, Andrey, et al.
Publicado: (2012)

An Insight into miR-1290: An Oncogenic miRNA with Diagnostic Potential
por: Guz, Małgorzata, et al.
Publicado: (2022)

Is miR-29 an oncogene or tumor suppressor in CLL?
por: Pekarsky, Yuri, et al.
Publicado: (2010)

Suppression of AGO2 by miR-132 as a determinant of miRNA-mediated silencing in human primary endothelial cells
por: Leonov, German, et al.
Publicado: (2015)

Acetylation-dependent regulation of BRAF oncogenic function
por: Dai, Xiangpeng, et al.
Publicado: (2022)

TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA
por: Li, You, et al.
Publicado: (2019)

MiR 208a Regulates Mitochondrial Biogenesis in Metabolically Challenged Cardiomyocytes
por: Mekala, Naveen, et al.
Publicado: (2021)

Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis
por: Lin, Xiaoping, et al.
Publicado: (2016)

Nuclear miR-122 directly regulates the biogenesis of cell survival oncomiR miR-21 at the posttranscriptional level
por: Wang, Dong, et al.
Publicado: (2018)

The proto-oncogene KRAS is targeted by miR-200c
por: Kopp, Florian, et al.
Publicado: (2013)

Oncogenic miR-9 is a target of erlotinib in NSCLCs
por: Chen, Xi, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_j9mr88ai3a9fdtdlqg65obuoub