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Diagnostic Challenge and Neuromuscular Junction Contribution to ALS Pathogenesis

Amyotrophic lateral sclerosis (ALS) represents the major adult-onset motor neuron disease. Both human and animal studies reveal the critical implication of muscle and neuromuscular junctions (NMJs) in the initial phase of this disease. Despite the common efforts, ALS diagnosis remains particularly c...

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Detalles Bibliográficos
Autores principales: Campanari, Maria-Letizia, Bourefis, Annis-Rayan, Kabashi, Edor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372519/
https://www.ncbi.nlm.nih.gov/pubmed/30787905
http://dx.doi.org/10.3389/fneur.2019.00068