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Diagnostic Challenge and Neuromuscular Junction Contribution to ALS Pathogenesis
Amyotrophic lateral sclerosis (ALS) represents the major adult-onset motor neuron disease. Both human and animal studies reveal the critical implication of muscle and neuromuscular junctions (NMJs) in the initial phase of this disease. Despite the common efforts, ALS diagnosis remains particularly c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372519/ https://www.ncbi.nlm.nih.gov/pubmed/30787905 http://dx.doi.org/10.3389/fneur.2019.00068 |