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ACE Insertion/Deletion Polymorphism (rs4646994) Is Associated With the Increased Risk of Multiple Myeloma

Introduction: The insertion (I allele) deletion (D allele) polymorphism of ACE gene (rs4646994) may influence the etiopathogenesis of multiple myeloma (MM). ACE gene is expressed in bone marrow cells and encodes angiotensin converting enzyme (ACE). It converts angiotensin I to active peptide angiote...

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Detalles Bibliográficos
Autores principales: Zmorzynski, Szymon, Szudy-Szczyrek, Aneta, Popek-Marciniec, Sylwia, Korszen-Pilecka, Iwona, Wojcierowska-Litwin, Magdalena, Luterek, Małgorzata, Chocholska, Sylwia, Styk, Wojciech, Swiderska-Kołacz, Grazyna, Januszewska, Joanna, Mielnik, Michal, Hus, Marek, Filip, Agata A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372536/
https://www.ncbi.nlm.nih.gov/pubmed/30788288
http://dx.doi.org/10.3389/fonc.2019.00044