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Effects of the Genetic Depletion of Polysialyltransferases on the Structure and Connectivity of Interneurons in the Adult Prefrontal Cortex

Polysialic acid (polySia) is a complex sugar that in the nervous system appears mainly as a posttranslational modification of the neural cell adhesion molecule (NCAM). PolySia plays important roles during brain development, but also in its plasticity during adulthood. Two polysialyltransferases (pol...

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Detalles Bibliográficos
Autores principales: Curto, Yasmina, Alcaide, Julia, Röckle, Iris, Hildebrandt, Herbert, Nacher, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372547/
https://www.ncbi.nlm.nih.gov/pubmed/30787870
http://dx.doi.org/10.3389/fnana.2019.00006