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On the Other Side: Manipulating the Immune Checkpoint Landscape of Dendritic Cells to Enhance Cancer Immunotherapy

Monoclonal antibodies targeting co-inhibitory immune checkpoint molecules have been successful in clinical trials of both solid and hematological malignancies as acknowledged by the 2018 Nobel Prize in Medicine, however improving clinical response rates is now key to expanding their efficacy in area...

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Detalles Bibliográficos
Autores principales: Kong, Benjamin Y., Bolton, Holly, Kim, Julius W., Silveira, Pablo A., Fromm, Phillip D., Clark, Georgina J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372550/
https://www.ncbi.nlm.nih.gov/pubmed/30788290
http://dx.doi.org/10.3389/fonc.2019.00050