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Maternal LINE-1 DNA Methylation and Congenital Heart Defects in Down Syndrome
Background: Down syndrome (DS) is one of the most common chromosomal abnormalities associated with congenital heart defects (CHD), with approximately 40 to 60% of cases showing cardiac defects. This study assessed (i) the association between maternal LINE-1 methylation and the occurrence of CHDs in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372553/ https://www.ncbi.nlm.nih.gov/pubmed/30787943 http://dx.doi.org/10.3389/fgene.2019.00041 |