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Maternal LINE-1 DNA Methylation and Congenital Heart Defects in Down Syndrome

Background: Down syndrome (DS) is one of the most common chromosomal abnormalities associated with congenital heart defects (CHD), with approximately 40 to 60% of cases showing cardiac defects. This study assessed (i) the association between maternal LINE-1 methylation and the occurrence of CHDs in...

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Detalles Bibliográficos
Autores principales: Babić Božović, Ivana, Stanković, Aleksandra, Živković, Maja, Vraneković, Jadranka, Mahulja-Stamenković, Vesna, Brajenović-Milić, Bojana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372553/
https://www.ncbi.nlm.nih.gov/pubmed/30787943
http://dx.doi.org/10.3389/fgene.2019.00041