Mutation S110L of H1N1 Influenza Virus Hemagglutinin: A Potent Determinant of Attenuation in the Mouse Model

Characterization of a pandemic 2009 H1N1 influenza virus isolated from a fatal case patient (F-IAV), showed the presence of three different mutations; potential determinants of its high pathogenicity that were located in the polymerase subunits (PB2 A221T and PA D529N) and the hemagglutinin (HA S110...

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Detalles Bibliográficos
Autores principales: Nieto, Amelia, Vasilijevic, Jasmina, Santos, Nuno Brito, Zamarreño, Noelia, López, Pablo, Amorim, Maria Joao, Falcon, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372558/
https://www.ncbi.nlm.nih.gov/pubmed/30787926
http://dx.doi.org/10.3389/fimmu.2019.00132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372558/
https://www.ncbi.nlm.nih.gov/pubmed/30787926
http://dx.doi.org/10.3389/fimmu.2019.00132

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