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Identification of Pre-symptomatic Gene Signatures That Predict Resilience to Cognitive Decline in the Genetically Diverse AD-BXD Model

Across the population, individuals exhibit a wide variation of susceptibility or resilience to developing Alzheimer’s disease (AD). Identifying specific factors that promote resilience would provide insight into disease mechanisms and nominate potential targets for therapeutic intervention. Here, we...

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Detalles Bibliográficos
Autores principales: Neuner, Sarah M., Heuer, Sarah E., Zhang, Ji-Gang, Philip, Vivek M., Kaczorowski, Catherine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372563/
https://www.ncbi.nlm.nih.gov/pubmed/30787942
http://dx.doi.org/10.3389/fgene.2019.00035