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The frequency of hepatotoxicity and myelotoxicity in leukemic children with different high doses of methotrexate

BACKGROUND AND OBJECTIVES: Methotrexate (MTX) is a chemotherapeutic agent that functions as a folic acid antagonist. The frequency of high dose methotrexate (HDMTX)-associated toxicity is variable. In this study, we investigated the frequency of myelotoxicity and hepatotoxicity 7 days after HDMTX in...

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Detalles Bibliográficos
Autores principales: Özdemir, Zeynep Canan, Bozkurt Turhan, Ayşe, Düzenli Kar, Yeter, Bör, Özcan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: King Faisal Specialist Hospital and Research Centre 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372565/
https://www.ncbi.nlm.nih.gov/pubmed/30805487
http://dx.doi.org/10.1016/j.ijpam.2016.08.008