Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site

Fusing antigens to chemokines to target antigen presenting cells (APC) is a promising method for enhancing immunogenicity of DNA vaccines. However, it is unclear how different chemokines compare in terms of immune potentiating effects. Here we compare Ccl3- and Xcl1-fusion vaccines containing hemagg...

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Detalles Bibliográficos
Autores principales: Lysén, Anna, Braathen, Ranveig, Gudjonsson, Arnar, Tesfaye, Demo Yemane, Bogen, Bjarne, Fossum, Even
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372594/
https://www.ncbi.nlm.nih.gov/pubmed/30755656
http://dx.doi.org/10.1038/s41598-018-38080-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372594/
https://www.ncbi.nlm.nih.gov/pubmed/30755656
http://dx.doi.org/10.1038/s41598-018-38080-7

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