Inhibition of upper small intestinal mTOR lowers plasma glucose levels by inhibiting glucose production

Glucose homeostasis is partly controlled by the energy sensor mechanistic target of rapamycin (mTOR) in the muscle and liver. However, whether mTOR in the small intestine affects glucose homeostasis in vivo remains unknown. Here, we first report that delivery of rapamycin or an adenovirus encoding t...

Descripción completa

Detalles Bibliográficos
Autores principales: Waise, T. M. Zaved, Rasti, Mozhgan, Duca, Frank A., Zhang, Song-Yang, Bauer, Paige V., Rhodes, Christopher J., Lam, Tony K. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372624/
https://www.ncbi.nlm.nih.gov/pubmed/30755615
http://dx.doi.org/10.1038/s41467-019-08582-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372624/
https://www.ncbi.nlm.nih.gov/pubmed/30755615
http://dx.doi.org/10.1038/s41467-019-08582-7

Ejemplares similares