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NKT Cells in Mice Originate from Cytoplasmic CD3-Positive, CD4(−)CD8(−) Double-Negative Thymocytes that Express CD44 and IL-7Rα
Although natural killer T cells (NKT cells) are thought to be generated from CD4(+)CD8(+) (DP) thymocytes, the developmental origin of CD4(−)CD8(−) (DN) NKT cells has remained unclear. In this study, we found the level of NK1.1 expression was highest in DN cells, followed by CD4 and CD8 (SP) and DP...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372634/ https://www.ncbi.nlm.nih.gov/pubmed/30755654 http://dx.doi.org/10.1038/s41598-018-37811-0 |