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NKT Cells in Mice Originate from Cytoplasmic CD3-Positive, CD4(−)CD8(−) Double-Negative Thymocytes that Express CD44 and IL-7Rα

Although natural killer T cells (NKT cells) are thought to be generated from CD4(+)CD8(+) (DP) thymocytes, the developmental origin of CD4(−)CD8(−) (DN) NKT cells has remained unclear. In this study, we found the level of NK1.1 expression was highest in DN cells, followed by CD4 and CD8 (SP) and DP...

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Detalles Bibliográficos
Autores principales:	Hu, Zhansheng, Gu, Wen, Wei, Yang, Liu, Gang, Wu, Shengli, Liu, Tie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372634/ https://www.ncbi.nlm.nih.gov/pubmed/30755654 http://dx.doi.org/10.1038/s41598-018-37811-0

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