Dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition

The monoamine neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts an inhibitory influence over motivation, but the circuits mediating this are unknown. Here, we used an optogenetic approach to isolate the contribution of dorsal raphe nucleus (DRN) 5-HT neurons and 5-HT innervation of the m...

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Detalles Bibliográficos
Autores principales: Browne, Caleb J., Abela, Andrew R., Chu, Duong, Li, Zhaoxia, Ji, Xiaodong, Lambe, Evelyn K., Fletcher, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372654/
https://www.ncbi.nlm.nih.gov/pubmed/30420603
http://dx.doi.org/10.1038/s41386-018-0271-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372654/
https://www.ncbi.nlm.nih.gov/pubmed/30420603
http://dx.doi.org/10.1038/s41386-018-0271-x

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