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Dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition
The monoamine neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts an inhibitory influence over motivation, but the circuits mediating this are unknown. Here, we used an optogenetic approach to isolate the contribution of dorsal raphe nucleus (DRN) 5-HT neurons and 5-HT innervation of the m...
Autores principales: | Browne, Caleb J., Abela, Andrew R., Chu, Duong, Li, Zhaoxia, Ji, Xiaodong, Lambe, Evelyn K., Fletcher, Paul J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372654/ https://www.ncbi.nlm.nih.gov/pubmed/30420603 http://dx.doi.org/10.1038/s41386-018-0271-x |
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