Revisit Population-based and Family-based Genotype Imputation

Genome-Wide Association (GWA) with population-based imputation (PBI) has been successful in identifying common variants associated with complex diseases; however, much heritability remains to be explained and low frequency variants (LFV) may contribute. To identify LFV, a study of unrelated individu...

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Detalles Bibliográficos
Autores principales: Liu, Ching-Ti, Deng, Xuan, Fisher, Virginia, Heard-Costa, Nancy, Xu, Hanfei, Zhou, Yanhua, Vasan, Ramachandran S., Cupples, L. Adrienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372660/
https://www.ncbi.nlm.nih.gov/pubmed/30755687
http://dx.doi.org/10.1038/s41598-018-38469-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372660/
https://www.ncbi.nlm.nih.gov/pubmed/30755687
http://dx.doi.org/10.1038/s41598-018-38469-4

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