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Revisit Population-based and Family-based Genotype Imputation
Genome-Wide Association (GWA) with population-based imputation (PBI) has been successful in identifying common variants associated with complex diseases; however, much heritability remains to be explained and low frequency variants (LFV) may contribute. To identify LFV, a study of unrelated individu...
Autores principales: | Liu, Ching-Ti, Deng, Xuan, Fisher, Virginia, Heard-Costa, Nancy, Xu, Hanfei, Zhou, Yanhua, Vasan, Ramachandran S., Cupples, L. Adrienne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372660/ https://www.ncbi.nlm.nih.gov/pubmed/30755687 http://dx.doi.org/10.1038/s41598-018-38469-4 |
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