Pathogenic function of bystander-activated memory-like CD4(+) T cells in autoimmune encephalomyelitis

T cells generate antigen-specific immune responses to their cognate antigen as a hallmark of adaptive immunity. Despite the importance of antigen-specific T cells, here we show that antigen non-related, bystander memory-like CD4(+) T cells also significantly contribute to autoimmune pathogenesis. Tr...

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Detalles Bibliográficos
Autores principales: Lee, Hong-Gyun, Lee, Jae-Ung, Kim, Do-Hyun, Lim, Sangho, Kang, Insoo, Choi, Je-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372661/
https://www.ncbi.nlm.nih.gov/pubmed/30755603
http://dx.doi.org/10.1038/s41467-019-08482-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372661/
https://www.ncbi.nlm.nih.gov/pubmed/30755603
http://dx.doi.org/10.1038/s41467-019-08482-w

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