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Pathogenic function of bystander-activated memory-like CD4(+) T cells in autoimmune encephalomyelitis
T cells generate antigen-specific immune responses to their cognate antigen as a hallmark of adaptive immunity. Despite the importance of antigen-specific T cells, here we show that antigen non-related, bystander memory-like CD4(+) T cells also significantly contribute to autoimmune pathogenesis. Tr...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372661/ https://www.ncbi.nlm.nih.gov/pubmed/30755603 http://dx.doi.org/10.1038/s41467-019-08482-w |