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Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors

The NLRP3 inflammasome is a multimeric protein complex that initiates an inflammatory form of cell death and triggers the release of proinflammatory cytokines IL-1β and IL-18. The NLRP3 inflammasome has been implicated in a wide range of diseases, including Alzheimer’s disease, Prion diseases, type...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Wang, Huanan, Kouadir, Mohammed, Song, Houhui, Shi, Fushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372664/
https://www.ncbi.nlm.nih.gov/pubmed/30755589
http://dx.doi.org/10.1038/s41419-019-1413-8