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Mitochondrial superoxide dismutase 2 mediates γ-irradiation-induced cancer cell invasion

Sublethal doses of γ-rays promote cancer cell invasion by stimulating a signaling pathway that sequentially involves p53, sulfatase 2 (SULF2), β-catenin, interleukin-6 (IL-6), signal transducer and activator of transcription 3 (STAT3), and Bcl-X(L). Given that Bcl-X(L) can increase O(2)(•−) producti...

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Detalles Bibliográficos
Autores principales: Jung, Chan-Hun, Kim, Eun Mi, Song, Jie-Young, Park, Jong Kuk, Um, Hong-Duck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372678/
https://www.ncbi.nlm.nih.gov/pubmed/30755594
http://dx.doi.org/10.1038/s12276-019-0207-5