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Hypoxia preconditioning promotes bone marrow mesenchymal stem cells survival by inducing HIF-1α in injured neuronal cells derived exosomes culture system

Bone marrow derived stem cells (BMSCs) transplantation are viewed as a promising therapeutic candidate for spinal cord injury (SCI). However, the inflammatory microenvironment in the spinal cord following SCI limits the survival and efficacy of transplanted BMSCs. In this study, we investigate wheth...

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Detalles Bibliográficos
Autores principales: Luo, Zucheng, Wu, Fangfang, Xue, Enxing, Huang, Linlin, Yan, Ping, Pan, Xiaoyun, Zhou, Yulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372680/
https://www.ncbi.nlm.nih.gov/pubmed/30755595
http://dx.doi.org/10.1038/s41419-019-1410-y