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Ghrelin Receptor Influence on Cocaine Reward is Not Directly Dependent on Peripheral Acyl-Ghrelin

The peptide hormone acyl-ghrelin and its receptor, GHSR(1a), represent intriguing therapeutic targets due to their actions in metabolic homeostasis and reward activity. However, this pleotropic activity makes it difficult to intervene in this system without inducing unwanted effects. Thus, it is des...

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Detalles Bibliográficos
Autores principales: Wenthur, Cody J., Gautam, Ritika, Zhou, Bin, Vendruscolo, Leandro F., Leggio, Lorenzo, Janda, Kim D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372697/
https://www.ncbi.nlm.nih.gov/pubmed/30755699
http://dx.doi.org/10.1038/s41598-019-38549-z