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Combined treatment with minodronate and vitamin C increases bone mineral density and strength in vitamin C-deficient rats

OBJECTIVES: Reduced bone quality caused by vitamin C deficiency in older persons may lead to incidental fragility fractures during bisphosphonate treatment, although bisphosphonate increases bone mineral density (BMD). This study aimed to evaluate the effects of minodronate and ascorbic acid (Aa) on...

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Detalles Bibliográficos
Autores principales: Segawa, Toyohito, Miyakoshi, Naohisa, Kasukawa, Yuji, Aonuma, Hiroshi, Tsuchie, Hiroyuki, Shimada, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Osteoporosis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372727/
https://www.ncbi.nlm.nih.gov/pubmed/30775465
http://dx.doi.org/10.1016/j.afos.2016.01.002