Nucleotide Resolution Comparison of Transcription of Human Cytomegalovirus and Host Genomes Reveals Universal Use of RNA Polymerase II Elongation Control Driven by Dissimilar Core Promoter Elements

The large genome of human cytomegalovirus (HCMV) is transcribed by RNA polymerase II (Pol II). However, it is not known how closely this betaherpesvirus follows host transcriptional paradigms. We applied PRO-Seq and PRO-Cap methods to profile and quantify transcription initiation and productive elon...

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Detalles Bibliográficos
Autores principales: Parida, Mrutyunjaya, Nilson, Kyle A., Li, Ming, Ball, Christopher B., Fuchs, Harrison A., Lawson, Christine K., Luse, Donal S., Meier, Jeffery L., Price, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372792/
https://www.ncbi.nlm.nih.gov/pubmed/30755505
http://dx.doi.org/10.1128/mBio.02047-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372792/
https://www.ncbi.nlm.nih.gov/pubmed/30755505
http://dx.doi.org/10.1128/mBio.02047-18

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