Cargando…

Herpes Simplex Virus 1 Lytic Infection Blocks MicroRNA (miRNA) Biogenesis at the Stage of Nuclear Export of Pre-miRNAs

Herpes simplex virus 1 (HSV-1) switches between two infection programs, productive (“lytic”) and latent infection. Some HSV-1 microRNAs (miRNAs) have been hypothesized to help control this switch, and yet little is known about regulation of their expression. Using Northern blot analyses, we found th...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Dongli, Li, Gang, Morris-Love, Jenna, Qi, Shuyuan, Feng, Lei, Mertens, Max E., Jurak, Igor, Knipe, David M., Coen, Donald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372804/
https://www.ncbi.nlm.nih.gov/pubmed/30755517
http://dx.doi.org/10.1128/mBio.02856-18