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Effects of combined therapy of alendronate and low-intensity pulsed ultrasound on metaphyseal bone repair after osteotomy in the proximal tibia of glucocorticoid-induced osteopenia rats

OBJECTIVES: Glucocorticoid (GC) treatment inhibits activation of runt-related transcription factor 2 (Runx2), which is essential for osteoblast differentiation from stem cells. As a result, GC treatment results in bone loss, GC-induced osteoporosis (GIO), elevated fracture risk, and delayed bone hea...

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Detalles Bibliográficos
Autores principales: Kawano, Tetsuya, Miyakoshi, Naohisa, Kasukawa, Yuji, Hongo, Michio, Tsuchie, Hiroyuki, Sato, Chie, Fujii, Masashi, Suzuki, Masazumi, Akagawa, Manabu, Ono, Yuichi, Yuasa, Yusuke, Nagahata, Itsuki, Shimada, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Osteoporosis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372826/
https://www.ncbi.nlm.nih.gov/pubmed/30775528
http://dx.doi.org/10.1016/j.afos.2017.11.001