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Could Alzheimer’s Disease Originate in the Periphery and If So How So?
The classical amyloid cascade model for Alzheimer’s disease (AD) has been challenged by several findings. Here, an alternative molecular neurobiological model is proposed. It is shown that the presence of the APOE ε4 allele, altered miRNA expression and epigenetic dysregulation in the promoter regio...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372984/ https://www.ncbi.nlm.nih.gov/pubmed/29705945 http://dx.doi.org/10.1007/s12035-018-1092-y |