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Atypical antipsychotics induce human osteoblasts apoptosis via Wnt/β-catenin signaling

BACKGROUND: There is evidence that atypical antipsychotics (APs) increase risk of osteoporosis in schizophrenia patients, however the mechanism is unclear. The aim of the study was to explore the molecular mechanisms about Wnt/β-catenin signal pathway underlying the osteal side effects of APs. METHO...

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Detalles Bibliográficos
Autores principales: Li, Peifan, Wang, Yiming, Liu, Xingde, Zhou, Zhen, Wang, Jun, Zhou, Haiyan, Zheng, Lei, Yang, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373048/
https://www.ncbi.nlm.nih.gov/pubmed/30755277
http://dx.doi.org/10.1186/s40360-019-0287-9