Active immunization with norovirus P particle-based amyloid-β chimeric protein vaccine induces high titers of anti-Aβ antibodies in mice

BACKGROUND: Active immunotherapy targeting amyloid-β (Aβ) is a promising treatment for Alzheimer’s disease (AD). Numerous preclinical studies and clinical trials demonstrated that a safe and effective AD vaccine should induce high titers of anti-Aβ antibodies while avoiding the activation of T cells...

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Detalles Bibliográficos
Autores principales: Yang, Ping, Guo, Yongqing, Sun, Yao, Yu, Bin, Zhang, Haihong, Wu, Jiaxin, Yu, Xianghui, Wu, Hui, Kong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373079/
https://www.ncbi.nlm.nih.gov/pubmed/30755174
http://dx.doi.org/10.1186/s12865-019-0289-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373079/
https://www.ncbi.nlm.nih.gov/pubmed/30755174
http://dx.doi.org/10.1186/s12865-019-0289-9

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