Streamlined computational pipeline for genetic background characterization of genetically engineered mice based on next generation sequencing data

BACKGROUND: Genetically engineered mice (GEM) are essential tools for understanding gene function and disease modeling. Historically, gene targeting was first done in embryonic stem cells (ESCs) derived from the 129 family of inbred strains, leading to a mixed background or congenic mice when crosse...

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Detalles Bibliográficos
Autores principales: Farkas, C., Fuentes-Villalobos, F., Rebolledo-Jaramillo, B., Benavides, F., Castro, A. F., Pincheira, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373082/
https://www.ncbi.nlm.nih.gov/pubmed/30755158
http://dx.doi.org/10.1186/s12864-019-5504-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373082/
https://www.ncbi.nlm.nih.gov/pubmed/30755158
http://dx.doi.org/10.1186/s12864-019-5504-9

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