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Oritavancin polymethylmethacrylate (PMMA)—compressive strength testing and in vitro elution

BACKGROUND: Polymethylmethacrylate (PMMA) is used for local antimicrobial delivery in orthopedic infection. Oritavancin is a long half-life lipoglycopeptide with broad activity against Gram-positive bacteria. Herein, we addressed if 7.5% w/w oritavancin mixed into PMMA affects PMMA strength and whet...

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Detalles Bibliográficos
Autores principales: Schmidt-Malan, Suzannah M., Greenwood-Quaintance, Kerryl E., Berglund, Lawrence J., Mandrekar, Jayawant, Patel, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373086/
https://www.ncbi.nlm.nih.gov/pubmed/30755223
http://dx.doi.org/10.1186/s13018-019-1080-6