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SHMT1 inhibits the metastasis of HCC by repressing NOX1-mediated ROS production
BACKGROUND: Hepatocellular carcinoma (HCC) is the most major type of primary hepatic cancer. Serine hydroxymethyltransferase 1 (SHMT1) is recently found to play critical roles in human cancers including lung cancer, ovarian cancer and intestinal cancer. However, the expression, function and the unde...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373090/ https://www.ncbi.nlm.nih.gov/pubmed/30755243 http://dx.doi.org/10.1186/s13046-019-1067-5 |