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SHMT1 inhibits the metastasis of HCC by repressing NOX1-mediated ROS production

BACKGROUND: Hepatocellular carcinoma (HCC) is the most major type of primary hepatic cancer. Serine hydroxymethyltransferase 1 (SHMT1) is recently found to play critical roles in human cancers including lung cancer, ovarian cancer and intestinal cancer. However, the expression, function and the unde...

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Detalles Bibliográficos
Autores principales:	Dou, Changwei, Xu, Qiuran, Liu, Jie, Wang, Yufeng, Zhou, Zhenyu, Yao, Weifeng, Jiang, Kai, Cheng, Jian, Zhang, Chengwu, Tu, Kangsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373090/ https://www.ncbi.nlm.nih.gov/pubmed/30755243 http://dx.doi.org/10.1186/s13046-019-1067-5

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