Different next-generation sequencing pipelines based detection of tumor DNA in cerebrospinal fluid of lung adenocarcinoma cancer patients with leptomeningeal metastases

BACKGROUND: The nucleic acid mutation status in intracranial metastasis is markedly significant clinically. The goal of the current study was to explore whether the tumor-associated mutations can be detected by different next-generation sequencing (NGS) pipelines in paired cerebrospinal fluid (CSF)...

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Detalles Bibliográficos
Autores principales: Ge, Mengxi, Zhan, Qiong, Zhang, Zhenzhen, Ji, Xiaoyu, Zhou, Xinli, Huang, Ruofan, Liang, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373107/
https://www.ncbi.nlm.nih.gov/pubmed/30755180
http://dx.doi.org/10.1186/s12885-019-5348-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373107/
https://www.ncbi.nlm.nih.gov/pubmed/30755180
http://dx.doi.org/10.1186/s12885-019-5348-3

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