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Human bone marrow-derived mesenchymal stem cells promote the growth and drug-resistance of diffuse large B-cell lymphoma by secreting IL-6 and elevating IL-17A levels

BACKGROUND: The drug-resistance and relapse of diffuse large B-cell lymphoma (DLBCL), which are related to mesenchymal stem cells (MSCs), have become increasingly common. However, the underlying mechanisms remain elusive. METHODS: CCK 8 assay, colony formation assay, and xenograft mouse model were u...

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Detalles Bibliográficos
Autores principales: Zhong, Weijie, Zhu, Zhigang, Xu, Xin, Zhang, Hui, Xiong, Huabao, Li, Qingshan, Wei, Yaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373150/
https://www.ncbi.nlm.nih.gov/pubmed/30755239
http://dx.doi.org/10.1186/s13046-019-1081-7