Cargando…

Human bone marrow-derived mesenchymal stem cells promote the growth and drug-resistance of diffuse large B-cell lymphoma by secreting IL-6 and elevating IL-17A levels

BACKGROUND: The drug-resistance and relapse of diffuse large B-cell lymphoma (DLBCL), which are related to mesenchymal stem cells (MSCs), have become increasingly common. However, the underlying mechanisms remain elusive. METHODS: CCK 8 assay, colony formation assay, and xenograft mouse model were u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhong, Weijie, Zhu, Zhigang, Xu, Xin, Zhang, Hui, Xiong, Huabao, Li, Qingshan, Wei, Yaming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373150/ https://www.ncbi.nlm.nih.gov/pubmed/30755239 http://dx.doi.org/10.1186/s13046-019-1081-7

Ejemplares similares

Increased interleukin-17A levels promote rituximab resistance by suppressing p53 expression and predict an unfavorable prognosis in patients with diffuse large B cell lymphoma
por: Zhong, Weijie, et al.
Publicado: (2018)

Construction of tandem diabody (IL-6/CD20)-secreting human umbilical cord mesenchymal stem cells and its experimental treatment on diffuse large B cell lymphoma
por: Zhang, Jiayi, et al.
Publicado: (2022)

IL-17B/IL-17RB signaling cascade contributes to self-renewal and tumorigenesis of cancer stem cells by regulating Beclin-1 ubiquitination
por: Bie, Qingli, et al.
Publicado: (2021)

Kaposi sarcoma herpesvirus (KSHV)-associated lymphomas are associated with markedly elevated serum IL-10, elevated IL-6, IL-17 and circulating KSHV
por: Uldrick, Thomas S, et al.
Publicado: (2012)

Detection and Isolation of Viable Mouse IL-17-Secreting T Cells
por: Foerster, Anna, et al.
Publicado: (2008)

IFN‐γ(+)IL‐17(+)Th17 cells regulate fibrosis through secreting IL‐21 in systemic scleroderma
por: Xing, Xiaojing, et al.
Publicado: (2020)

Bone marrow-derived mesenchymal stem cell-secreted IL-8 promotes the angiogenesis and growth of colorectal cancer
por: Wang, Jiancheng, et al.
Publicado: (2015)

Effect of IL-34 on T helper 17 cell proliferation and IL-17 secretion by peripheral blood mononuclear cells from rheumatoid arthritis patients
por: Li, Xin, et al.
Publicado: (2020)

Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion
por: Noack, Mélissa, et al.
Publicado: (2016)

IL-17 and IL-17-producing cells in protection versus pathology
por: Mills, Kingston H. G.
Publicado: (2022)

Expression Level of IL-6 Secreted by Bone Marrow Stromal Cells in Mice with Aplastic Anemia
por: Chen, Yong Feng, et al.
Publicado: (2013)

Modulation of Cytokine Secretion Allows CD4 T Cells Secreting IL-10 and IL-17 to Simultaneously Participate in Maintaining Tolerance and Immunity
por: Saito, Kanako, et al.
Publicado: (2015)

Increased IL-17RA and IL-17RC in End-Stage COPD and the Contribution to Mast Cell Secretion of FGF-2 and VEGF
por: Roos, Abraham B., et al.
Publicado: (2017)

The Human IL-23 Decoy Receptor Inhibits T-Cells Producing IL-17 by Genetically Engineered Mesenchymal Stem Cells
por: Rostami, Masoumeh, et al.
Publicado: (2018)

IL-17 and IL-22 in Cerebrospinal Fluid and Plasma Are Elevated in Guillain-Barré Syndrome
por: Li, Shujuan, et al.
Publicado: (2012)

IL-17 Inhibits Chondrogenic Differentiation of Human Mesenchymal Stem Cells
por: Kondo, Masahiro, et al.
Publicado: (2013)

2D Visualization of the Psoriasis Transcriptome Fails to Support the Existence of Dual-Secreting IL-17A/IL-22 Th17 T Cells
por: Le, Stephanie T., et al.
Publicado: (2019)

Interleukin (IL)-12 and IL-18 Synergize to Promote MAIT Cell IL-17A and IL-17F Production Independently of IL-23 Signaling
por: Cole, Suzanne, et al.
Publicado: (2020)

Serum concentrations of IL-17A, IL-17B, IL-17E and IL-17F in patients with systemic sclerosis
por: Robak, Ewa, et al.
Publicado: (2019)

IL-17A Secreted by Th17 Cells Is Essential for the Host against Streptococcus agalactiae Infections
por: Chen, Jing, et al.
Publicado: (2021)

Clinical Significance of IL-23 Regulating IL-17A and/or IL-17F Positive Th17 Cells in Chronic Periodontitis
por: Luo, Zhenhua, et al.
Publicado: (2014)

HVEM Promotes the Osteogenesis of allo-MSCs by Inhibiting the Secretion of IL-17 and IFN-γ in Vγ4T Cells
por: He, Lei, et al.
Publicado: (2021)

Continued Elevation of Plasma IL-4 and IL-17 Predicts the Progression from VMC to DCM
por: Wang, Z. H., et al.
Publicado: (2020)

IL17/IL17RA as a Novel Signaling Axis Driving Mesenchymal Stem Cell Therapeutic Function in Experimental Autoimmune Encephalomyelitis
por: Kurte, Mónica, et al.
Publicado: (2018)

IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells
por: Coccia, Margherita, et al.
Publicado: (2012)

Bone marrow derived-mesenchymal stem cells downregulate IL17A dependent IL6/STAT3 signaling pathway in CCl(4)-induced rat liver fibrosis
por: Farouk, Shimaa, et al.
Publicado: (2018)

Hypoxia regulates IL-17A secretion from nasal polyp epithelial cells
por: Xiu, Qian, et al.
Publicado: (2017)

Interaction with Mesenchymal Stem Cells Provokes Natural Killer Cells for Enhanced IL-12/IL-18-Induced Interferon-Gamma Secretion
por: Thomas, Heike, et al.
Publicado: (2014)

Notch-Hes1 Signaling Regulates IL-17A(+)γδ(+)T Cell Expression and IL-17A Secretion of Mouse Psoriasis-Like Skin Inflammation
por: Wang, Yanqin, et al.
Publicado: (2020)

Responses of Multipotent Retinal Stem Cells to IL-1β, IL-18, or IL-17
por: Chen, Shida, et al.
Publicado: (2015)

IL-6 and TGF-β-Secreting Adoptively-Transferred Murine Mesenchymal Stromal Cells Accelerate Healing of Psoriasis-like Skin Inflammation and Upregulate IL-17A and TGF-β
por: Cuesta-Gomez, Nerea, et al.
Publicado: (2023)

Interleukin 17 (IL-17)-Induced Mesenchymal Stem Cells Prolong the Survival of Allogeneic Skin Grafts
por: Ma, Tengxiao, et al.
Publicado: (2018)

Elevated levels of anti inflammatory IL-10 and pro inflammatory IL-17 in malignant pleural effusions
por: Klimatsidas, Michail, et al.
Publicado: (2012)

Mobilization permits reliable ELISPOT detection of long-term memory T cells secreting IFN-γ, IL-4, IL-5, and IL-17 without in vitro expansion
por: Ghosh, Jaya, et al.
Publicado: (2013)

Characteristic Pattern of IL-17RA, IL-17RB, and IL-17RC in Monocytes/Macrophages and Mast Cells From Patients With Bullous Pemphigoid
por: Nesmond, Stéphane, et al.
Publicado: (2019)

IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling
por: Goepfert, Arnaud, et al.
Publicado: (2022)

Additive or Synergistic Interactions Between IL-17A or IL-17F and TNF or IL-1β Depend on the Cell Type
por: Noack, Mélissa, et al.
Publicado: (2019)

The Effect of Secreted IL-10 from Mesenchymal Stem Cell on Immune Checkpoint Molecules
por: Sari, Mutiara Indah, et al.
Publicado: (2023)

IL‐17 alters the mesenchymal stem cell niche towards osteogenesis in cooperation with osteocytes
por: Liao, Chongshan, et al.
Publicado: (2019)

Increased Circulating Th17 Cells, Serum IL-17A, and IL-23 in Takayasu Arteritis
por: Misra, Durga Prasanna, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_rqup2p5hihlodamvm2tevf0opg