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Induced expression of GINS complex is an essential step for reactivation of quiescent stem-like tumor cells within the peri-necrotic niche in human glioblastoma
PURPOSE: Glioblastoma is still intractable despite the progress in therapies, and the intractability is attributable to a minor population of stem-like tumor cells. As a niche harboring quiescent stem-like tumor cells with potentially high tumorigenicity, we have specified an area around large ische...
Autores principales: | Kimura, Tokuhiro, Cui, Dan, Kawano, Hiroo, Yoshitomi-Sakamoto, Chihiro, Takakura, Nobuyuki, Ikeda, Eiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373247/ https://www.ncbi.nlm.nih.gov/pubmed/30465075 http://dx.doi.org/10.1007/s00432-018-2797-z |
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