Mechanisms of cell death induced by arginase and asparaginase in precursor B-cell lymphoblasts

Arginase has therapeutic potential as a cytotoxic agent in some cancers, but this is unclear for precursor B acute lymphoblastic leukaemia (pre-B ALL), the commonest form of childhood leukaemia. We compared arginase cytotoxicity with asparaginase, currently used in pre-B ALL treatment, and character...

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Detalles Bibliográficos
Autores principales: Métayer, Lucy E., Brown, Richard D., Carlebur, Saskia, Burke, G. A. Amos, Brown, Guy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373273/
https://www.ncbi.nlm.nih.gov/pubmed/30578463
http://dx.doi.org/10.1007/s10495-018-1506-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373273/
https://www.ncbi.nlm.nih.gov/pubmed/30578463
http://dx.doi.org/10.1007/s10495-018-1506-3

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