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Mechanisms of cell death induced by arginase and asparaginase in precursor B-cell lymphoblasts
Arginase has therapeutic potential as a cytotoxic agent in some cancers, but this is unclear for precursor B acute lymphoblastic leukaemia (pre-B ALL), the commonest form of childhood leukaemia. We compared arginase cytotoxicity with asparaginase, currently used in pre-B ALL treatment, and character...
Autores principales: | Métayer, Lucy E., Brown, Richard D., Carlebur, Saskia, Burke, G. A. Amos, Brown, Guy C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373273/ https://www.ncbi.nlm.nih.gov/pubmed/30578463 http://dx.doi.org/10.1007/s10495-018-1506-3 |
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