Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus

Systemic lupus erythematosus (SLE, OMIM 152700) is a systemic autoimmune disease with a complex etiology. The mode of inheritance of the genetic risk beyond familial SLE cases is currently unknown. Additionally, the contribution of heterozygous variants in genes known to cause monogenic SLE is not f...

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Detalles Bibliográficos
Autores principales: Almlöf, Jonas Carlsson, Nystedt, Sara, Leonard, Dag, Eloranta, Maija-Leena, Grosso, Giorgia, Sjöwall, Christopher, Bengtsson, Anders A., Jönsen, Andreas, Gunnarsson, Iva, Svenungsson, Elisabet, Rönnblom, Lars, Sandling, Johanna K., Syvänen, Ann-Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373277/
https://www.ncbi.nlm.nih.gov/pubmed/30707351
http://dx.doi.org/10.1007/s00439-018-01966-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373277/
https://www.ncbi.nlm.nih.gov/pubmed/30707351
http://dx.doi.org/10.1007/s00439-018-01966-7

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