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A novel T-cell epitope in the transmembrane region of the hepatitis B virus envelope protein responds upon dendritic cell expansion

Restoring antiviral immunity is a promising immunotherapeutic approach to the treatment of chronic hepatitis B virus (HBV) infection. Dendritic cells play a crucial role in triggering antiviral immunity. In this study, we identified immunodominant epitopes prevalent in CD8(+) T cell responses. We ch...

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Detalles Bibliográficos
Autores principales: Chen, Lubiao, Zhang, Ying, Zhang, Shaoquan, Chen, Youming, Shu, Xin, Lai, Jing, Cao, Hong, Lian, Yifan, Stamataki, Zania, Huang, Yuehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373280/
https://www.ncbi.nlm.nih.gov/pubmed/30415392
http://dx.doi.org/10.1007/s00705-018-4095-0