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PET imaging of noradrenaline transporters in Parkinson’s disease: focus on scan time

OBJECTIVE: In subjects with idiopathic Parkinson’s disease (PD) the functional state of the locus coeruleus and the subtle derangements in the finely tuned dopamine–noradrenaline interplay are largely unknown. The PET ligand (S,S)-[(11)C]-O-methylreboxetine (C-11 MRB) has been described to reliably...

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Detalles Bibliográficos
Autores principales: Brumberg, Joachim, Tran-Gia, Johannes, Lapa, Constantin, Isaias, Ioannis U., Samnick, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373329/
https://www.ncbi.nlm.nih.gov/pubmed/30293197
http://dx.doi.org/10.1007/s12149-018-1305-5