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Deficiency of the clock gene Bmal1 affects neural progenitor cell migration

We demonstrate the impact of a disrupted molecular clock in Bmal1-deficient (Bmal1(−/−)) mice on migration of neural progenitor cells (NPCs). Proliferation of NPCs in rostral migratory stream (RMS) was reduced in Bmal1(−/−) mice, consistent with our earlier studies on adult neurogenesis in hippocamp...

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Detalles Bibliográficos
Autores principales: Ali, Amira A. H., Schwarz-Herzke, Beryl, Mir, Shakila, Sahlender, Benita, Victor, Marion, Görg, Boris, Schmuck, Martin, Dach, Katharina, Fritsche, Ellen, Kremer, Andreas, von Gall, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373387/
https://www.ncbi.nlm.nih.gov/pubmed/30341743
http://dx.doi.org/10.1007/s00429-018-1775-1