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Selective JAKinibs: Prospects in Inflammatory and Autoimmune Diseases

Cytokines, many of which signal through the JAK–STAT (Janus kinase–Signal Transducers and Activators of Transcription) pathway, play a central role in the pathogenesis of inflammatory and autoimmune diseases. Currently three JAK inhibitors have been approved for clinical use in USA and/or Europe: to...

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Detalles Bibliográficos
Autores principales: T. Virtanen, Anniina, Haikarainen, Teemu, Raivola, Juuli, Silvennoinen, Olli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373396/
https://www.ncbi.nlm.nih.gov/pubmed/30701418
http://dx.doi.org/10.1007/s40259-019-00333-w